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• Activity deltas table
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Motif ID: FOX{D1,D2}.p2

Z-value: 1.569

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr10_+_111985628	1.322	NM_005962	MXI1	MAX interactor 1
chr10_+_111969988	1.315	NM_001008541	MXI1	MAX interactor 1
chr17_+_58755158	1.014	NM_001099432 NM_017679	BCAS3	breast carcinoma amplified sequence 3
chr18_+_66465316	0.956	NM_024781	CCDC102B	coiled-coil domain containing 102B
chr6_+_89791510	0.927		PNRC1	proline-rich nuclear receptor coactivator 1
chr19_+_18496966	0.838	NM_004864	GDF15	growth differentiation factor 15
chr12_-_92539614	0.834	NM_001731	BTG1	B-cell translocation gene 1, anti-proliferative
chr17_+_9745847	0.709		GLP2R	glucagon-like peptide 2 receptor
chr6_-_88875766	0.660	NM_001160226 NM_001160258 NM_001160259 NM_016083	CNR1	cannabinoid receptor 1 (brain)
chr11_-_72504643	0.646	NM_006645	STARD10	StAR-related lipid transfer (START) domain containing 10
chr10_+_23728197	0.640	NM_001145373	OTUD1	OTU domain containing 1
chr16_-_30107492	0.624	NM_031477 NM_001145524	YPEL3	yippee-like 3 (Drosophila)
chr11_-_104916041	0.612	NM_001017534 NM_052889	CARD16	caspase recruitment domain family, member 16
chr4_-_2263706	0.581	NM_006454	MXD4	MAX dimerization protein 4
chr1_+_145438437	0.579	NM_006472	TXNIP	thioredoxin interacting protein
chr21_+_30517897	0.575		C21orf7	chromosome 21 open reading frame 7
chr10_+_99079017	0.569	NM_005479	FRAT1	frequently rearranged in advanced T-cell lymphomas
chr7_+_106809405	0.567	NM_001244262 NM_012257	HBP1	HMG-box transcription factor 1
chr9_-_3223007	0.562
chr12_-_10573041	0.558	NM_002261 NM_007333	KLRC3	killer cell lectin-like receptor subfamily C, member 3
chr19_+_1207129	0.556		EFNA2	ephrin-A2
chr17_-_26662439	0.537	NM_174887	IFT20	intraflagellar transport 20 homolog (Chlamydomonas)
chr13_+_97874704	0.535		MBNL2	muscleblind-like 2 (Drosophila)
chr7_-_112579726	0.533	NM_152556	C7orf60	chromosome 7 open reading frame 60
chr17_+_57408907	0.531	NM_001005404	YPEL2	yippee-like 2 (Drosophila)
chr9_-_98269480	0.515	NM_001083607	PTCH1	patched 1
chr1_+_229440128	0.512	NM_006542	SPHAR	S-phase response (cyclin related)
chr7_+_30174343	0.505	NM_152793	C7orf41	chromosome 7 open reading frame 41
chr17_-_66951381	0.501	NM_007168	ABCA8	ATP-binding cassette, sub-family A (ABC1), member 8
chr9_+_12775713	0.501		C9orf150	chromosome 9 open reading frame 150
chr13_-_41240607	0.500	NM_002015	FOXO1	forkhead box O1
chr14_-_74551073	0.473		ALDH6A1	aldehyde dehydrogenase 6 family, member A1
chr9_+_118916069	0.466	NM_002581	PAPPA	pregnancy-associated plasma protein A, pappalysin 1
chr4_+_134073180	0.462		PCDH10	protocadherin 10
chr8_+_70405027	0.459	NM_001128205 NM_001128206	SULF1	sulfatase 1
chr10_-_21186530	0.444	NM_006393	NEBL	nebulette
chr19_-_47734215	0.442	NM_014417	BBC3	BCL2 binding component 3
chr14_-_74551159	0.440	NM_005589	ALDH6A1	aldehyde dehydrogenase 6 family, member A1
chr19_+_12902295	0.438	NM_002229	JUNB	jun B proto-oncogene
chr22_-_31686707	0.431		PIK3IP1	phosphoinositide-3-kinase interacting protein 1
chr17_-_80656461	0.419	NM_006822	RAB40B	RAB40B, member RAS oncogene family
chr12_-_10588543	0.415	NM_002260	KLRC2 KLRC3	killer cell lectin-like receptor subfamily C, member 2 killer cell lectin-like receptor subfamily C, member 3
chr3_-_141868208	0.409	NM_001178138 NM_001178139	TFDP2	transcription factor Dp-2 (E2F dimerization partner 2)
chr17_+_39394269	0.394	NM_031963	KRTAP9-8	keratin associated protein 9-8
chr10_-_90750955	0.388	NM_001141945	ACTA2	actin, alpha 2, smooth muscle, aorta
chr19_-_11564568	0.386		ELAVL3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)
chr8_+_70405080	0.386		SULF1	sulfatase 1
chr3_+_23987514	0.384	NM_001145425	NR1D2	nuclear receptor subfamily 1, group D, member 2
chr15_-_63449479	0.382	NM_015920	RPS27L	ribosomal protein S27-like
chrX_-_106960028	0.382		TSC22D3	TSC22 domain family, member 3
chrX_-_106960268	0.382	NM_004089	TSC22D3	TSC22 domain family, member 3
chr9_-_94124194	0.380	NM_001698	AUH	AU RNA binding protein/enoyl-CoA hydratase
chr14_+_24584467	0.379	NM_181357	DCAF11	DDB1 and CUL4 associated factor 11
chr14_+_24584009	0.375		DCAF11	DDB1 and CUL4 associated factor 11
chr8_-_28243941	0.369	NM_018660	ZNF395	zinc finger protein 395
chr14_+_24583905	0.365	NM_001163484	DCAF11	DDB1 and CUL4 associated factor 11
chr14_+_24583979	0.363	NM_025230	DCAF11	DDB1 and CUL4 associated factor 11
chr14_+_23067128	0.362	NM_022060	ABHD4	abhydrolase domain containing 4
chr19_-_18654280	0.356		FKBP8	FK506 binding protein 8, 38kDa
chr6_+_72922513	0.355	NM_001168407 NM_001168408	RIMS1	regulating synaptic membrane exocytosis 1
chr3_+_54156691	0.355	NM_018398	CACNA2D3	calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr2_+_86947429	0.352		RMND5A	required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr7_+_129008044	0.349		AHCYL2	adenosylhomocysteinase-like 2
chr8_+_99956630	0.349	NM_001142462 NM_053001	OSR2	odd-skipped related 2 (Drosophila)
chr5_+_78531848	0.348	NM_152405	JMY	junction mediating and regulatory protein, p53 cofactor
chr9_-_98269686	0.344	NM_001083606	PTCH1	patched 1
chr19_-_18653680	0.342		FKBP8	FK506 binding protein 8, 38kDa
chr4_+_86396251	0.341	NM_001025616	ARHGAP24	Rho GTPase activating protein 24
chr1_+_33722158	0.340	NM_152493	ZNF362	zinc finger protein 362
chr6_+_139094656	0.340	NM_015439	CCDC28A	coiled-coil domain containing 28A
chr1_+_227127959	0.337		ADCK3	aarF domain containing kinase 3
chr14_+_24584321	0.336		DCAF11	DDB1 and CUL4 associated factor 11
chr12_+_12764755	0.333	NM_001310	CREBL2	cAMP responsive element binding protein-like 2
chr7_+_90339146	0.330		CDK14	cyclin-dependent kinase 14
chr11_+_63137260	0.328	NM_080866	SLC22A9	solute carrier family 22 (organic anion transporter), member 9
chr12_-_53343607	0.326		KRT8	keratin 8
chr22_-_31688329	0.324	NM_001135911 NM_052880	PIK3IP1	phosphoinositide-3-kinase interacting protein 1
chr12_-_53074172	0.324	NM_006121	KRT1	keratin 1
chr12_+_12764844	0.324		CREBL2	cAMP responsive element binding protein-like 2
chr12_+_120740123	0.319	NM_012240	SIRT4	sirtuin 4
chr6_-_134373618	0.317	NM_145176	SLC2A12	solute carrier family 2 (facilitated glucose transporter), member 12
chr10_-_91405320	0.317	NM_148977	PANK1	pantothenate kinase 1
chr1_+_227127993	0.317		ADCK3	aarF domain containing kinase 3
chr11_+_73359734	0.316	NM_001130036	PLEKHB1	pleckstrin homology domain containing, family B (evectins) member 1
chr16_-_2827128	0.314	NM_007108 NM_207013	TCEB2	transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
chr13_-_86373328	0.313	NM_032229	SLITRK6	SLIT and NTRK-like family, member 6
chr11_-_34535302	0.311	NM_001243080 NM_001422	ELF5	E74-like factor 5 (ets domain transcription factor)
chr2_+_86947570	0.310		RMND5A	required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr16_-_28550227	0.309		NUPR1	nuclear protein, transcriptional regulator, 1
chr13_-_49975734	0.307	NM_030925	CAB39L	calcium binding protein 39-like
chr4_-_152149042	0.304	NM_001243349	SH3D19	SH3 domain containing 19
chr12_+_69201979	0.304		MDM2	Mdm2 p53 binding protein homolog (mouse)
chr1_-_45956795	0.302	NM_007170	TESK2	testis-specific kinase 2
chr5_-_36301999	0.302	NM_001161429 NM_145000	RANBP3L	RAN binding protein 3-like
chr12_+_69201845	0.299	NM_002392	MDM2	Mdm2 p53 binding protein homolog (mouse)
chr6_-_155777036	0.299	NM_015718	NOX3	NADPH oxidase 3
chr1_+_196788860	0.298	NM_002113	CFHR1	complement factor H-related 1
chr3_+_54156573	0.292		CACNA2D3	calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr11_-_117747331	0.292		FXYD6	FXYD domain containing ion transport regulator 6
chr1_+_86934525	0.290	NM_001285	CLCA1	chloride channel accessory 1
chr1_+_227127999	0.289		ADCK3	aarF domain containing kinase 3
chr1_+_227127937	0.287	NM_020247	ADCK3	aarF domain containing kinase 3
chr21_+_30671736	0.286	NM_206866	BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr8_+_120079423	0.284	NM_006438	COLEC10	collectin sub-family member 10 (C-type lectin)
chr9_-_88897372	0.281	NM_030940	ISCA1	iron-sulfur cluster assembly 1 homolog (S. cerevisiae)
chr20_+_54823787	0.280	NM_019888	MC3R	melanocortin 3 receptor
chr11_-_62314199	0.272		AHNAK	AHNAK nucleoprotein
chr4_-_141075232	0.272	NM_018717	MAML3	mastermind-like 3 (Drosophila)
chr3_-_57234279	0.270	NM_003865	HESX1	HESX homeobox 1
chr5_-_169724614	0.264		LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr3_+_23986735	0.263	NM_005126	NR1D2	nuclear receptor subfamily 1, group D, member 2
chr3_-_114343052	0.261	NM_001164347	ZBTB20	zinc finger and BTB domain containing 20
chr2_+_132480063	0.261	NM_013310	C2orf27A	chromosome 2 open reading frame 27A
chr17_+_57642885	0.260	NM_001166301 NM_024612	DHX40	DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr16_-_4664894	0.259	NM_145253	FAM100A	family with sequence similarity 100, member A
chr2_+_86947387	0.257	NM_022780	RMND5A	required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr20_-_1309809	0.256	NM_080489	SDCBP2	syndecan binding protein (syntenin) 2
chr19_+_18111923	0.255	NM_001025604	ARRDC2	arrestin domain containing 2
chr17_+_38219040	0.254	NM_001190918 NM_003250 NM_199334	THRA	thyroid hormone receptor, alpha
chr2_-_26205437	0.251	NM_002254	KIF3C	kinesin family member 3C
chr19_+_50380681	0.248	NM_001168222 NM_024682	TBC1D17	TBC1 domain family, member 17
chr19_-_3061245	0.247		AES	amino-terminal enhancer of split
chr17_-_39165343	0.243	NM_031958	KRTAP3-1	keratin associated protein 3-1
chr6_+_122793061	0.241	NM_181794	PKIB	protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr1_-_198510074	0.237	NM_133262 NM_133326	ATP6V1G3	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
chr20_-_34241830	0.237	NM_003915	CPNE1	copine I
chr10_+_48255223	0.236	NM_001040084 NM_001098845	ANXA8L2 ANXA8 ANXA8L1	annexin A8-like 2 annexin A8 annexin A8-like 1
chr1_+_150122095	0.235	NM_016274	PLEKHO1	pleckstrin homology domain containing, family O member 1
chr14_-_73493744	0.235	NM_021260	ZFYVE1	zinc finger, FYVE domain containing 1
chr5_+_40841296	0.234	NM_032587	CARD6	caspase recruitment domain family, member 6
chrX_+_70315637	0.233	NM_001170931 NM_005938	FOXO4	forkhead box O4
chr14_-_76448091	0.233	NM_003239	TGFB3	transforming growth factor, beta 3
chr12_+_6875686	0.232		PTMS	parathymosin
chr2_+_12856813	0.229	NM_021643	TRIB2	tribbles homolog 2 (Drosophila)
chr14_-_65569056	0.227		MAX	MYC associated factor X
chrX_-_48937457	0.227		WDR45	WD repeat domain 45
chrX_-_62780748	0.226		LOC92249	uncharacterized LOC92249
chr12_-_9268440	0.225		A2M	alpha-2-macroglobulin
chr7_-_27135524	0.225	NM_005522 NM_153620	HOXA1	homeobox A1
chr5_-_150460599	0.225	NM_001252385 NM_001252386 NM_001252393 NM_006058	TNIP1	TNFAIP3 interacting protein 1
chr12_-_31479120	0.224	NM_001135811 NM_021238 NM_001135812	FAM60A	family with sequence similarity 60, member A
chr14_+_74551655	0.222	NM_001024674	LIN52	lin-52 homolog (C. elegans)
chr14_-_65569221	0.221	NM_002382 NM_145112 NM_145113 NM_145114 NM_145116 NM_197957	MAX	MYC associated factor X
chr18_+_61575203	0.220		SERPINB10	serpin peptidase inhibitor, clade B (ovalbumin), member 10
chrX_-_48937560	0.220	NM_001029896	WDR45	WD repeat domain 45
chr12_-_7245048	0.219		C1R	complement component 1, r subcomponent
chr20_+_62887046	0.217	NM_001104925 NM_018257	PCMTD2	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
chr1_+_150122415	0.217		PLEKHO1	pleckstrin homology domain containing, family O member 1
chr5_-_150460550	0.216		TNIP1	TNFAIP3 interacting protein 1
chr10_-_99094427	0.213	NM_012083	FRAT2	frequently rearranged in advanced T-cell lymphomas 2
chr12_-_9268513	0.213		A2M	alpha-2-macroglobulin
chr6_-_30043547	0.213	NM_170769 NM_025236	RNF39	ring finger protein 39
chr1_-_161102367	0.212		DEDD	death effector domain containing
chr14_+_105266878	0.212	NM_001137601	ZBTB42	zinc finger and BTB domain containing 42
chr1_+_3541550	0.209	NM_182752	TPRG1L	tumor protein p63 regulated 1-like
chr2_-_198175458	0.209		ANKRD44	ankyrin repeat domain 44
chr12_-_7245006	0.208	NM_001733	C1R	complement component 1, r subcomponent
chr17_+_67410825	0.205	NM_002758	MAP2K6	mitogen-activated protein kinase kinase 6
chr20_+_21106623	0.203	NM_001163022 NM_001163023 NM_018474	PLK1S1	polo-like kinase 1 substrate 1
chr18_+_9475528	0.198	NM_006788	RALBP1	ralA binding protein 1
chr2_-_26205327	0.197		KIF3C	kinesin family member 3C
chr19_-_18902077	0.197	NM_000095	COMP	cartilage oligomeric matrix protein
chr10_-_45474210	0.196	NM_007021	C10orf10	chromosome 10 open reading frame 10
chr17_-_36831156	0.196	NM_001130677	C17orf96	chromosome 17 open reading frame 96
chrX_-_135863502	0.196	NM_004840	ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr12_-_9268522	0.195	NM_000014	A2M	alpha-2-macroglobulin
chr1_+_150122246	0.192		PLEKHO1	pleckstrin homology domain containing, family O member 1
chr4_-_103682126	0.192		MANBA	mannosidase, beta A, lysosomal
chr21_+_30671217	0.191	NM_001186	BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr1_-_161102457	0.190	NM_001039711 NM_032998	DEDD	death effector domain containing
chr10_+_99400469	0.189		PI4K2A	phosphatidylinositol 4-kinase type 2 alpha
chr19_-_50316360	0.189	NM_001171937 NM_025129	FUZ	fuzzy homolog (Drosophila)
chr6_-_33168163	0.187		RXRB	retinoid X receptor, beta
chr2_-_208890207	0.187	NM_001080475	PLEKHM3	pleckstrin homology domain containing, family M, member 3
chr3_-_93692898	0.187	NM_000313	PROS1	protein S (alpha)
chr10_-_90712510	0.186	NM_001613	ACTA2	actin, alpha 2, smooth muscle, aorta
chr17_+_3379295	0.186	NM_000049	ASPA	aspartoacylase
chr3_-_93692592	0.184		PROS1	protein S (alpha)
chr19_+_859658	0.184	NM_001928	CFD	complement factor D (adipsin)
chr9_-_94124149	0.183		AUH	AU RNA binding protein/enoyl-CoA hydratase
chr1_-_161102210	0.181	NM_001039712	DEDD	death effector domain containing
chr7_-_140340575	0.181		DENND2A	DENN/MADD domain containing 2A
chr1_+_151170978	0.181	NM_001135636 NM_001135637 NM_001135638 NM_003557	PIP5K1A	phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
chr2_-_69098502	0.180	NM_014482	BMP10	bone morphogenetic protein 10
chr9_-_130667571	0.180		LOC100131355 ST6GALNAC6	uncharacterized LOC100131355 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr12_-_31479038	0.180		FAM60A	family with sequence similarity 60, member A
chr13_-_28543143	0.177		CDX2	caudal type homeobox 2
chr5_-_40756009	0.176	NM_012382	TTC33	tetratricopeptide repeat domain 33
chr17_-_45973142	0.176
chr12_-_57704245	0.176	NM_014925	R3HDM2	R3H domain containing 2
chr21_+_30671227	0.175		BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr15_+_81589240	0.175	NM_004513	IL16	interleukin 16
chr20_-_50179338	0.174		NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr16_-_28550324	0.173	NM_001042483 NM_012385	NUPR1	nuclear protein, transcriptional regulator, 1
chrX_-_136113832	0.173	NM_054021	GPR101	G protein-coupled receptor 101
chr14_+_24867926	0.171	NM_025081	NYNRIN	NYN domain and retroviral integrase containing
chr1_-_1356823	0.171	NM_001145210 NM_001243535 NM_001243536	ANKRD65	ankyrin repeat domain 65
chr7_+_129007942	0.169	NM_001130723	AHCYL2	adenosylhomocysteinase-like 2
chr11_+_33061560	0.168	NM_001145541	TCP11L1	t-complex 11 (mouse)-like 1
chr3_-_187452669	0.167	NM_001134738	BCL6	B-cell CLL/lymphoma 6

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.70	6.43e-04	GO:0001071	nucleic acid binding transcription factor activity
1.70	6.43e-04	GO:0003700	sequence-specific DNA binding transcription factor activity
1.99	1.93e-02	GO:0003712	transcription cofactor activity
1.98	2.05e-02	GO:0000988	protein binding transcription factor activity
1.98	2.05e-02	GO:0000989	transcription factor binding transcription factor activity
1.67	4.80e-02	GO:0043565	sequence-specific DNA binding